Bulletin, trained by Todd Pletcher and ridden by Javier Castellano, opened the proceedings with a scintillating victory in the US$1 million Juvenile Turf Sprint.
Owned by a consortium including WinStar Farm and China Horse Club International, Bulletin became the first horse to win a Breeders' Cup race after just one prior career start -- a seventh length victory at Gulfstream Park in September.
"Very impressed with what he did," said Castellano, who rode his ninth Breeders' Cup winner. "Second time of his career -- very professional."
Bulletin broke sharply out of the gate and took quick command of the 5 1/2-furlong race.
"Fantastic way to start," Pletcher said. "He broke really well and was sharp. He took it to them the whole way."
Chelsea Cloisters, trained by Wesley Ward and ridden by Tyler Gaffalione was second and the Aidan O'Brien-trained So Perfect was third with Wayne Lordan in the irons.
"They went really quick out there," Lordan said. "He came home really well and he has run a great race."